Best Hotels in Greenville MS

We checked thousands of reviews on and to find the best hotels for your stay
Go to Hotel List View map

Katerina Kore

Updated: 25 January 2024 · 4 min

Nestled in the heart of the Mississippi Delta, Greenville is a city rich in history, culture, and Southern charm. it serves as a warm, welcoming destination for travelers. Within its boundaries, a selection of hotels awaits, promising comfortable accommodations that cater to the needs and budgets of every visitor.

Choosing the right hotel in Greenville plays a crucial role in the overall experience of your trip. Whether you're here to explore the historic sites, attend a blues festival, or simply soak in the scenic views of the Mississippi River, finding a hotel that aligns with your itinerary is paramount. Our recommendations will guide you through the top Greenville MS hotels, each offering unique amenities and services, ensuring your stay is both memorable and gratifying.

From luxury accommodations to budget-friendly options, Greenville hotels are designed to enhance your visit. Insightful tips and essential information about each property will help you make an informed decision, ensuring your comfort and convenience. Embark on a journey through Greenville's welcoming streets, and let the right hotel serve as your home away from home, providing a restful haven after a day of exploration and discovery.
Show more + Show less -

Our Top 8

(Sorted by rating & number of reviews)

1. Tru By Hilton Greenville
2. Holiday Inn Express And Suites Greenville
3. Econo Lodge Greenville
4. Rodeway Inn
5. Americas Best Value Inn & Suites Greenville
6. Hampton Inn Greenville
7. Harlows Casino Resort And Spa
8. Holiday Inn Express And Suites Greenville

Family-Friendly Greenville MS Hotels

Check Availability

Greenville
Mar 23, 2026 - Mar 24, 2026

Tru By Hilton Greenville

7.6

Good

(371 Reviews)

+ 34 photos
At Tru by Hilton Greenville, guests are treated to an array of leisure facilities designed for fun and relaxation. The hotel features a large, inviting lobby with a game zone, perfect for unwinding after a day of exploring Greenville. A state-of-the-art fitness center caters to guests looking to maintain their workout routine, while the outdoor pool provides a refreshing escape. The vibrant, modern rooms offer a comfortable retreat with all the necessary amenities. This hotel's mix of leisure options and cozy accommodations makes it an attractive choice for those seeking a balanced and enjoyable stay.
Address: 600 Rayner Road
Rating: Good 7.6 (371 Reviews)
Rooms: 84
Price: From 161$

Holiday Inn Express And Suites Greenville

+ 44 photos
The Holiday Inn Express and Suites Greenville promises a seamless and comfortable experience for families. This hotel is praised for its spacious rooms and suites, offering ample space for families to spread out and relax. The indoor pool is a highlight, providing year-round entertainment for children, while the fitness center allows parents to stay active. Guests can enjoy a complimentary breakfast with a variety of hot and cold items, catering to different dietary needs and preferences. Its strategic location near major attractions and eateries adds to its appeal for families seeking convenience and fun. This hotel's commitment to providing a warm, welcoming environment makes it a top choice for families visiting Greenville.
Address: 3090 Highway 82 East
Rooms: 73
Price: From 169$

Budget-Friendly Greenville MS Hotels

For travelers keeping an eye on their wallets, Greenville offers a variety of hotels that blend affordability with comfort and convenience. This section features Greenville MS hotels that are perfect for budget-conscious visitors who don’t want to compromise on quality. These accommodations provide essential amenities like free WiFi, comfortable rooms, and locations close to Greenville's attractions. Staying at one of these hotels means you can save money without sacrificing a pleasant and comfortable visit to Greenville.

Econo Lodge Greenville

6.0

Good

(144 Reviews)

+ 47 photos
Econo Lodge Greenville offers travelers a budget-friendly option without sacrificing comfort and convenience. This hotel delivers essential amenities such as complimentary breakfast and free WiFi, ensuring a value-packed stay. Rooms are clean, comfortable, and equipped with refrigerators and microwaves, adding to the convenience for guests. Located near local attractions, Econo Lodge makes it easy for guests to explore Greenville without breaking the bank. The friendly staff and efficient service further enhance the overall experience, making it an excellent choice for cost-conscious travelers seeking a dependable stay in Greenville.
Address: 3080 Us 82 E.
Rating: Good 6.0 (144 Reviews)
Rooms: 77
Price: From 67$

Rodeway Inn

2.5

Good

(4 Reviews)

+ 49 photos
Rodeway Inn welcomes budget-conscious travelers with open arms, providing a comfortable place to rest without straining their wallets. This hotel is known for its clean, cozy rooms that feature all the necessary amenities for a pleasant stay, including free WiFi and comfortable bedding. Guests can enjoy a complimentary continental breakfast, adding to the value. Its strategic location allows easy access to Greenville's highlights, making it an ideal base for exploring the area. The combination of affordability, comfort, and convenience makes Rodeway Inn a great option for travelers looking to make the most of their visit to Greenville without overspending.
Address: 137 N. Walnut Street
Rating: Good 2.5 (4 Reviews)
Rooms: 99
Price: From 79$

Greenville MS Hotels with Exceptional Dining

Culinary enthusiasts will be delighted to know that Greenville offers hotels with exceptional dining experiences. This section of our guide is dedicated to Greenville MS hotels that stand out not only for their comfortable accommodations but also for their remarkable on-site dining options. These hotels cater to guests who appreciate the convenience of enjoying exquisite meals without having to leave the comfort of their hotel. From fine dining to casual eateries, these accommodations ensure that your culinary needs are met with style and quality.

Americas Best Value Inn & Suites Greenville

6.1

Good

(89 Reviews)

+ 19 photos
At Americas Best Value Inn & Suites Greenville, guests can enjoy a comfortable stay that combines affordability with essential amenities. This hotel stands out for its spacious rooms and convenient in-room features like microwaves and refrigerators, ensuring a hassle-free stay. A complimentary breakfast offers a satisfying start to the day, while free WiFi keeps guests connected. The hotel's location near Greenville’s attractions and dining options adds to its appeal for travelers looking to maximize their budget. With its commitment to providing excellent value, Americas Best Value Inn & Suites is a smart choice for visitors seeking both comfort and economy in Greenville.
Address: 2700 Highway 82 East
Rating: Good 6.1 (89 Reviews)
Rooms: 80
Price: From 66$

Hampton Inn Greenville

+ 41 photos
The Hampton Inn Greenville is not just about comfortable stays; it’s about offering guests a chance to relax and enjoy their time off. With an outdoor pool set in a beautifully landscaped area, guests can soak up the Mississippi sun or enjoy a leisurely swim. The fitness center is equipped with modern machines for a comprehensive workout. Each morning, guests can indulge in a hot, complimentary breakfast, a perfect start to a day of relaxation or exploration. The convenient location near local attractions and dining options allows for easy access to Greenville’s entertainment and leisure activities, making the Hampton Inn an excellent choice for leisure travelers.
Address: 1155 Vfw Road
Rooms: 76
Price: From 185$

Greenville MS Hotels for Business Travelers

Business travelers in Greenville can look forward to accommodations that blend seamless connectivity, comfort, and convenience. This section uncovers hotels perfectly suited for those on work trips, featuring essential amenities like high-speed internet, meeting spaces, and quiet rooms for maximum productivity. These establishments not only cater to your professional needs but also ensure a restful and invigorating stay, allowing you to focus on your work and unwind in equal measure.

Harlows Casino Resort And Spa

+ 28 photos
Business meets pleasure at Harlow's Casino Resort and Spa, where guests can enjoy a unique mix of entertainment and work facilities. This hotel offers versatile meeting spaces and a business center, complemented by high-speed internet access, making it easy to host business events or conferences. After work, guests can relax in the spa, enjoy dining at one of the on-site restaurants, or even try their luck at the casino. The comfortable rooms provide a sanctuary for rest, ensuring you're recharged for the next day. Its location adds an extra layer of convenience for guests looking to engage in leisure activities or explore the vibrant culture of Greenville post-work.
Address: 4280 Harlows Blvd
Rooms: 105
Price: From 119$

Holiday Inn Express And Suites Greenville

+ 44 photos
For those seeking a blend of work and comfort, the Holiday Inn Express and Suites Greenville provides the perfect setting. This hotel is equipped with a 24-hour business center, meeting facilities, and free high-speed internet, catering to the needs of modern business travelers. Rooms are designed for relaxation, with ergonomic workstations allowing guests to work comfortably. The indoor pool and fitness center offer leisure options to unwind. A hot Express Start breakfast is served daily, empowering you for the day ahead. Its proximity to major Greenville business venues makes it a convenient and smart choice for professionals.
Address: 3090 Highway 82 East
Rooms: 73
Price: From 169$

Greenville MS Hotels with Great Leisure Facilities

For those looking to enjoy downtime during their stay in Greenville certain hotels stand out with their excellent leisure facilities. This section details accommodations offering more than just a place to sleep, with amenities like swimming pools, fitness centers, and spas. These hotels are perfect for travelers who prioritize relaxation and fun as much as comfort and convenience, ensuring a memorable and rejuvenating stay.