Top Hotels Close to Mayo Clinic Jacksonville

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Katerina Kore

Updated: 09 January 2024 · 2 min

Jacksonville stands as a beacon of warmth, not just in its climate but through the hospitality it extends to visitors from all corners of the globe. Nestled within this vibrant city is the renowned Mayo Clinic, a destination for those seeking top-tier medical care and expertise. For those making the journey, finding the right accommodation is crucial, blending the need for proximity to the clinic with the desire for comfort and relaxation.

The search for hotels near the Mayo Clinic in Jacksonville is more than just about finding a place to stay; it's about ensuring peace of mind during a potentially stressful time. Fortunately, Jacksonville boasts an array of hotels that cater to every preference and budget, all within easy reach of the clinic. These accommodations not only promise a restful retreat but also provide convenient access to the myriad attractions Jacksonville has to offer, ensuring guests have a comfortable base to explore from or relax in.

Selecting the ideal hotel near the Mayo Clinic involves more than considering distance. It's about finding those places that offer supportive amenities such as flexible booking options, serene environments, and shuttle services to the clinic. With these considerations in mind, this article aims to guide you through the best hotels near Mayo Clinic in Jacksonville, offering insights and recommendations to make your stay as stress-free and comfortable as possible, whether you're visiting for medical reasons or supporting someone who is.
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Our Top 3

(Sorted by rating & number of reviews)

1. Baymont By Wyndham Jacksonville
2. Best Western Jacksonville Inn
3. Super 8 By Wyndham Jacksonville

Budget-Friendly Hotels Near Mayo Clinic Jacksonville, FL

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Jacksonville
Mar 23, 2026 - Mar 24, 2026

Baymont By Wyndham Jacksonville

7.7

Good

(81 Reviews)

+ 60 photos
Baymont By Wyndham Jacksonville is a haven for guests seeking comfortable accommodations close to the Mayo Clinic without stretching their budget. This hotel provides a welcoming atmosphere with spacious rooms, each fitted with modern comforts such as flat-screen TVs, free Wi-Fi, and comfortable bedding. Guests can start their day with a free continental breakfast and unwind in the outdoor pool or take advantage of the fitness center. Its location not only offers easy access to the Mayo Clinic but also to Jacksonville's vibrant dining and shopping venues. The Baymont By Wyndham Jacksonville ensures a balanced experience of comfort, convenience, and cost-efficiency, making it a favorite among budget-conscious travelers.
Address: 1914 Southbrooke Road
Rating: Good 7.7 (81 Reviews)
Rooms: 62
Price: From 55$

Comfort and Care Hotels Near Mayo Clinic Jacksonville, FL

When visiting the Mayo Clinic in Jacksonville, comfort and care are paramount, especially after a long day of appointments or procedures. This section is dedicated to hotels that go the extra mile in providing exceptional service, therapeutic comfort, and thoughtful amenities. These properties understand the unique needs of their guests, offering services such as complimentary shuttle services to the Mayo Clinic, rooms designed for relaxation and recuperation, and staff trained to accommodate medical patients and their families with empathy and care. Here, we will introduce three hotels renowned for their focus on guest comfort and support, ensuring a restful and nurturing environment during your stay.

Best Western Jacksonville Inn

8.3

Good

(197 Reviews)

+ 129 photos
Best Western Jacksonville Inn offers a prime combination of comfort, convenience, and affordability for visitors to the Mayo Clinic. Located just a short drive from the clinic, this hotel ensures guests can easily travel back and forth between appointments. Each room is designed with relaxation in mind, featuring comfortable beds, free high-speed internet, and a variety of modern amenities to make your stay as comfortable as possible. Additionally, guests can enjoy a complimentary breakfast, an outdoor pool, and a fitness center, allowing for a pleasant stay without breaking the bank. The hotel's friendly staff is always on hand to assist with any needs, making Best Western Jacksonville Inn a top choice for those seeking budget-friendly accommodations.
Address: 1709 W Morton Avenue
Rating: Good 8.3 (197 Reviews)
Rooms: 56
Price: From 65$

Super 8 By Wyndham Jacksonville

7.3

Good

(90 Reviews)

+ 41 photos
Super 8 By Wyndham Jacksonville stands out for its exceptional value and proximity to the Mayo Clinic, making it an ideal base for medical visitors and their families. This hotel ensures a hassle-free stay with free Wi-Fi, complimentary breakfast, and cozy rooms equipped with microwaves and refrigerators for added convenience. It prides itself on offering simple yet comfortable accommodations, where guests can rest and recharge after a day at the clinic. Furthermore, the friendly staff are knowledgeable about the area and can provide directions and recommendations to make your Jacksonville experience as smooth as possible. For those looking for affordability without sacrificing comfort, Super 8 By Wyndham Jacksonville is a dependable choice.
Address: 1003 W Morton Ave
Rating: Good 7.3 (90 Reviews)
Rooms: 43
Price: From 62$